We have multiple clients at Jonah & Associates whose sites are based on WordPress. Infact, our official website itself runs on wordpress. Instead of updating wordpress, optimizing it and fixing plugins issues in mutiple wordpress installations, We wanted to manage it all through just one wordpress installation.
We wanted to host it on a nice beefed up server that could handle millions of hits per week. So, after a bit of research, I’ve managed to spot the right articles that highlights just how to do this. It includes step by step guide from Henshaw (Raventools) who manages to even write updated security fixes with the use of his method. Check it out if you are looking for similar solution.
How to Easily Manage Multiple WordPress Sites With One Database and One Code Base.